New PDF release: Ageing : the paradox of life

By Robin Holliday

ISBN-10: 1402056400

ISBN-13: 9781402056406

For hundreds of years humans were questioned through the inevitability of human getting older. for many of the second one half the 20th century getting older remained a secret, or an unsolved organic challenge. on the finish of the 20 th century a striking clinical discovery emerged. It was once now not a unmarried discovery within the traditional experience, since it used to be in line with a chain of significant interconnected insights over fairly a protracted time period. those insights made it attainable for the first actual time to appreciate the organic purposes for getting older in animals and guy. it might already be stated, even if, that the various observations and insights that specify getting older usually are not accredited as proven wisdom for a very long time. the sphere continues to be jam-packed with scientists, and non-scientists, who're simply chuffed to head on speculating in regards to the 'mystery' of getting older. the purpose of this ebook is to dispel lack of knowledge by way of explaining in non-technical language what are the explanations for getting older and the parable of over the top prolongation of lifestyles.

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Extra resources for Ageing : the paradox of life

Sample text

But we never see the other theoretical possibilities, namely, animals which grow and breed quickly with long lifespans; and animals which grow and breed slowly with short lifespans. The former is a physiological impossibility, and the latter would lead to rapid extinction. Allocation of the resources available to a mammalian species Normal functions Biochemical synthesis Metabolism Respiration Cell turnover Movement Feeding and digestion Excretion Reproductive functions Gonads, gametes and sex Development Gestation Suckling Care of offspring Maintenance functions All those discussed and listed in Chapter 3 The above conclusions can be best applied within particular taxonomic groups, such as mammals, or birds.

On our death certificate a single cause of death may be given, but the reality is that if we did not die from one cause, we would die from another. The fact that one organ-system fails first, should not blind us to the fact that there is a multiplicity of changes occurring in molecules, cells, tissue and organs during ageing. Chapter 5. The Ancient Origins of Ageing Not all organism age. It is well established that populations of bacteria or yeast can go on growing forever, as long as nutrients are provided.

40 Chapter 5 Consider two animals A and B. A can reproduce sexually, and also has a body which can maintain itself indefinitely, by replacement of somatic cells as required. B can only reproduce sexually, and its body consists of non-dividing cells which will age and die. In an ideal environment A might do better, because it can survive and reproduce indefinitely, where B can only reproduce for a limited period of time. In Darwinian terms A appears to be fitter than B. Therefore, one might think, ageing could not evolve.

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Ageing : the paradox of life by Robin Holliday

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