By Hiram Gilbert
This moment version maintains to innovatively evaluation the hardest ideas in biochemistry for max comprehension in a quick time period. not like traditional texts or overview books that rigidity memorizing proof, simple innovations stresses the gaining knowledge of of primary strategies, in order that the reader really comprehends the fabric and feels cozy making use of it. Dr. Gilbert makes use of uncomplicated, jargon-free language and award-winning instructing ideas together with algorithms, mnemonics and medical examples.
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Extra info for Basic Concepts in Biochemistry - A Student's Survival Guide
Since they are attached in the ER and Golgi compartments, the sugar BG McGraw-Hill: Gilbert, Basic Concepts in Biochemistry, JN 5036 3 • Membranes and Membrane Proteins 27 • coating will point outward from the cell (will be on the outside surface of the membrane). Membrane proteins as well as phospholipids and glycolipids are embedded in the lipid bilayer and move around in the plane of the bilayer very rapidly. MEMBRANE FLUIDITY Increasing fluidity makes lateral diffusion faster. Fluidity increases with increased temperature, increased content of short-chain fatty acids, and increased content of cis-fatty acids.
The sign here can be confusing—it’s a convention. Having higher concentration outside than inside is considered favorable. If something moves from higher to lower concentration, that’s in the favorable direction and will contribute a negative ⌬G. The ⌬G is independent of whether or not the molecule is charged. If the species has a charge on it, there’s another ⌬G associated with moving it through a membrane. ⌬Gion ϭ zFV Here z is the charge, F is the faraday (23 kcal/V/mol), and V is the potential difference (voltage) across the membrane.
As the smoke slowly clears, we have a copy of the original DNA. Since all DNA polymerases require a primer and work only in the 5Ј to 3Ј direction, there’s a problem with replicating the 5Ј ends of the DNA. If an RNA primer has to be laid down and later removed, these ends can’t get replicated. For bacteria with a circular genome, this isn’t a problem. Eukaryotes have specialized structures called telomeres at the BG McGraw-Hill: Gilbert, Basic Concepts in Biochemistry, JN 5036 5 Expression of Genetic Information • 45 • ends of the chromosome to solve this problem.
Basic Concepts in Biochemistry - A Student's Survival Guide by Hiram Gilbert